Transcranial magnetic stimulation, tinnitus and auditory hallucinations

Abstract

Transcranial magnetic stimulation (TMS) has been shown to be effective in modulating cerebral cortex activity. Most of the published controlled studies have reported that left temporoparietal area stimulation with 1 Hz frequencies has managed to improve auditory hallucinations at least partially and transiently in patients suffering from schizophrenia. These stimulation parameters have been demonstrated to be useful in otologic patients with tinnitus sensation. The clinical relevance of these findings has already been discussed. However, in spite of the clinical benefit of TMS for these or other patients, it is revealing new data and new questions about the neurobiological basis of mental disorders. For example: which is the common substrate in tinnitus and auditory hallucinations that could explain such a therapeutic coincidence? In this work we present two representative clinic cases and we discuss this question.