Main points: 1. The traditional Chinese medicine An Shen Jiao Tai Yi Zhi decoction could improve the sleep quality of patients with Parkinson’s disease and promote changes in sleep structure. 2. Patients with Parkinson’s disease and sleep disorders exhibit reduced inflammatory response after treatment with An Shen Jiao Tai Yi Zhi decoction. 3. An Shen Jiao Tai Yi Zhi decoction has few adverse reactions and is highly safe.