Psoriasis and lithium treatment: a common physiopathology?
Keywords:
psoriasis, lithium, bipolar disorder, second messengers, side effectsAbstract
Introduction. Lithium is the main treatment of bipolar disorder. Lithium may produce several dermatological side effects including psoriasis.
Patient.A 42 years old female with bipolar disorder and psoriasis produced by lithium.The evolution of psoriasis was parallel to treatment with lithium.
Result.Psoriasis was resolved when lithium was replaced with carbamazepine and valproic acid.These medication shave different pharmacodynamic effects than lithium.
Conclusions. The effect of lithium on second messengers as etiological factor in the evolution of psoriasis in this patient were discussed.